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Submit ReviewClofibrate
说明： PPAR agonist
化学名： Ethyl 2-(4-chlorophenoxy)-2-methylpropionate
生物活性 for Clofibrate
Clofibrate is a PPAR agonist (EC50 values are 50, 500 and > 100 μM at PPARα, PPARγ and PPARδ respectively). Antihyperlipoproteinemic.
技术数据 for Clofibrate
| 分子量 | 242.7017 |
| 公式 | C12H15ClO3 |
| 储存 | Store at RT |
| CAS Number | 637-07-0 |
| PubChem ID | 2796 |
| InChI Key | KNHUKKLJHYUCFP-UHFFFAOYSA-N |
| Smiles | ClC1=CC=C(OC(C)(C)C(OCC)=O)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Clofibrate
参考文献 for Clofibrate
参考文献是支持产品生物活性的出版物。
Bishop-Bailey (2000) Peroxisome proliferator-activated receptors in the cardiovascular system. Br.J.Pharmacol. 129 823 PMID: 10696077
Shepherd (1993) Mechanism of action of fibrates. Postgrad.Med.J. 69 S34 PMID: 8497455
Willson et al (2000) The PPARs: from orphan receptors to drug discovery. J.Med.Chem. 43 527 PMID: 10691680
Merck Index 12 2437
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关键词: Clofibrate, Clofibrate supplier, PPAR, agonists, Non-Selective, Peroxisome, Proliferator-activating, Receptors, Non-selective, 0824, Tocris Bioscience
⚠ WARNING: This product can expose you to chemicals including Clofibrate, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov
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