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Submit ReviewGuvacine hydrochloride
说明： Specific GABA uptake inhibitor
化学名： 1,2,5,6-Tetrahydropyridine-3-carboxylic acid hydrochloride
纯度： ≥99% (HPLC)
生物活性 for Guvacine hydrochloride
Specific GABA uptake inhibitor. IC50 values are 14, 58, 119 and 1870 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.
技术数据 for Guvacine hydrochloride
| 分子量 | 163.6 |
| 公式 | C6H9NO2.HCl |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 6027-91-4 |
| PubChem ID | 11957555 |
| InChI Key | FGNUNVVTHHKDAM-UHFFFAOYSA-N |
| Smiles | Cl.O=C(C=1CNCCC1)O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Guvacine hydrochloride
参考文献 for Guvacine hydrochloride
参考文献是支持产品生物活性的出版物。
Borden et al (1994) Tiagabine, SK&F 89976-A, CI 966, and NNC-711 are selective for the cloned GABA transporter GAT-1. Eur.J.Pharmacol. 269 219 PMID: 7851497
Krogsgaard-Larsen et al (1978) Structure-activity studies on the inhibition of GABA binding to rat brain membranes by muscimol and related compounds. J.Neurochem. 30 1377 PMID: 670980
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关键词: Guvacine hydrochloride, Guvacine hydrochloride supplier, Specific, GABA, reuptake, inhibitors, inhibits, BGT-1, GAT, Transporters, Monoamine, Neurotransmitter, 0234, Tocris Bioscience
1 篇 Guvacine hydrochloride 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Guvacine hydrochloride 的部分引用包括：
Edwards et al (2011) Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2). Biochim Biophys Acta 1808 260 PMID: 20691150
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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