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Irbesartan

Cat. No. 5798 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Potent AT1 antagonist
化学名： 2-Butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Irbesartan

Irbesartan is a potent angiotensin II type 1 receptor (AT1) antagonist (IC50 = 1.3 nM). Displays antihypertensive activity. Orally bioavailable.

化合物库 for Irbesartan

Irbesartan is also offered as part of the Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。

技术数据 for Irbesartan

分子量 428.53
公式 C25H28N6O
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 138402-11-6
PubChem ID 3749
InChI Key YOSHYTLCDANDAN-UHFFFAOYSA-N
Smiles O=C(C1(CCCC1)N=C2CCCC)N2CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Irbesartan

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 42.85 100
ethanol 4.29 10

制备储备液 for Irbesartan

以下数据基于产品分子量 428.53。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.33 mL 11.67 mL 23.34 mL
5 mM 0.47 mL 2.33 mL 4.67 mL
10 mM 0.23 mL 1.17 mL 2.33 mL
50 mM 0.05 mL 0.23 mL 0.47 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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参考文献 for Irbesartan

参考文献是支持产品生物活性的出版物。

Burnier et al (2001) Angiotensin II type 1 receptor blockers. Circulation 103 904 PMID: 11171802

If you know of a relevant reference for Irbesartan, please let us know.

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关键词: Irbesartan, Irbesartan supplier, Potent, angiotensin, II, type, 1, receptor, antagonists, AT1, antihypertensive, orally, bioavailable, Angiotensin, Receptors, 5798, Tocris Bioscience

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