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Submit ReviewL-Glutathione Reduced
说明： Endogenous antioxidant
别名： GSH
化学名： L-γ-glutamyl-L-cysteinyl-glycine
纯度： ≥98%
生物活性 for L-Glutathione Reduced
L-Glutathione Reduced is an endogenous antioxidant; reduces reactive oxygen species formed during cellular metabolism. Regulates activity of the redox sensitive transcription factor NF-κB. Cytoprotective.
技术数据 for L-Glutathione Reduced
| 分子量 | 307.32 |
| 公式 | C10H17N3O6S |
| 储存 | Store at +4°C |
| 纯度 | ≥98% |
| CAS Number | 70-18-8 |
| PubChem ID | 124886 |
| InChI Key | RWSXRVCMGQZWBV-WDSKDSINSA-N |
| Smiles | O=C(N[C@@H](CS)C(NCC(O)=O)=O)CC[C@H](N)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for L-Glutathione Reduced
参考文献 for L-Glutathione Reduced
参考文献是支持产品生物活性的出版物。
Sen et al (1999) Glutathione homeostasis in response to exercise training and nutritional supplements. Mol.Cell.Biochem. 196 31 PMID: 10448900
Kerksick et al (2005) The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress. J.Int.Soc.Sports Nutr. 2 38 PMID: 18500954
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关键词: L-Glutathione Reduced, L-Glutathione Reduced supplier, Endogenous, antioxidant, NF-κB, cellular, metabolism, redox, cytoprotective, neuroprotective, GSH, Antioxidants, Amino, Acids, 5219, Tocris Bioscience
1 篇 L-Glutathione Reduced 的引用文献
引用文献是使用了 Tocris 产品的出版物。 L-Glutathione Reduced 的部分引用包括：
Das et al (2017) Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling. Sci Rep 7 40773 PMID: 28112165
L-Glutathione Reduced 的评论
平均评分: 5 (基于 3 条评论。)
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Great product.
By
Anonymous on 07/02/2019
种属： Human
used at 14mM aq. solution for kinetics experiments.
used it for generating a reducing environment in-vitro
GSH did not inhibit the LPA induced expression of pAMPK in microglia..
By
lisha joshi on 06/18/2019
分析类型： In Vitro
种属： Mouse
细胞系/组织： BV2 microglia cells
GSH was used at a concentration 10µM and was well tolerated by the cells. BV2 cells were pre incubated with the inhibitor for one and then treated with 1µM LPA. Western blot analysis revealed that GSH incubation did not abolish the LPA induced expression of pAMPK in BV2 microglia cells.
GSH inhibits 15d-PGJ2-induced apoptosis in osteosarcoma cells.
By
Christopher Trummer on 10/15/2018
分析类型： In Vitro
种属： Human
细胞系/组织： MG-63 osteosarcoma cells
MG-63 cells were incubated with GSH (10 μM) for 30 min prior to 15d-PGJ2 treatment (20 μM) for 24 h to follow apoptotic markers using Western blot. GSH inhibited 15d-PGJ2-induced PARP and Caspase-3 cleavage.
