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1-Hex-GlcNAlk

Cat. No. 7751 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Metabolic chemical reporter for studying glycosylation and glycoproteins
化学名： (2S,3R,4R,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(pent-4-ynamido)tetrahydro-2H-pyran-2-yl hexanoate
纯度： ≥95% (HPLC)
说明书
引用文献
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生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for 1-Hex-GlcNAlk

1-Hex-GlcNAlk is a metabolic chemical reporter (MCR) for studying glycoproteins and glycosylation; it comprises GlcNAlk functionalized at the anomeric position with hexanoic acid. 1-Hex-GlcNAlk exhibits time- and concentration-dependent specific enzymatic labeling of proteins in HeLa cells, with negligible background labeling detected in cell lysates.

技术数据 for 1-Hex-GlcNAlk

分子量 357.4
公式 C17H27NO7
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 2863607-71-8
InChI Key PJQZXSANZZIQIK-YFTGLANFSA-N
Smiles OC[C@H]1O[C@@H](OC(CCCCC)=O)[C@H](NC(CCC#C)=O)[C@@H](O)[C@@H]1O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 1-Hex-GlcNAlk

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 35.74 100

制备储备液 for 1-Hex-GlcNAlk

以下数据基于产品分子量 357.4。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.8 mL 13.99 mL 27.98 mL
5 mM 0.56 mL 2.8 mL 5.6 mL
10 mM 0.28 mL 1.4 mL 2.8 mL
50 mM 0.06 mL 0.28 mL 0.56 mL

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参考文献 for 1-Hex-GlcNAlk

参考文献是支持产品生物活性的出版物。

Pedowitz et al (2021) Anomeric fatty acid functionalization prevents nonenzymatic S-glycosylation by monosaccharide metabolic chemical reporters. ACS Chem Biol 16 1924 PMID: 34282887

If you know of a relevant reference for 1-Hex-GlcNAlk, please let us know.

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关键词: 1-Hex-GlcNAlk, 1-Hex-GlcNAlk supplier, glycosylation, glycoproteins, probes, bio-orthogonal, labeling, labelling, metabolic, chemical, reporter, MCR, Glycobiology, Probes, Post-translational, Modifications, 7751, Tocris Bioscience

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