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4-Thiouridine

Cat. No. 7005 2 篇引用文献 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Photoreactive uridine analog for RNA sequencing
化学名： 4-Thiouridine
纯度： ≥98% (HPLC)
说明书
引用文献 (2)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for 4-Thiouridine

4-Thiouridine is a photoreactive uridine analog for RNA sequencing (RNA seq) and thiol(SH)-linked alkylation for the metabolic sequencing of RNA (SLAM seq). Used as a crosslinker to identify RNA binding proteins. Is incorporated into newly transcribed RNA and can be used to track RNA from synthesis to degradation.

技术数据 for 4-Thiouridine

分子量 260.26
公式 C9H12N2O5S
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 13957-31-8
PubChem ID 3032615
InChI Key ZLOIGESWDJYCTF-XVFCMESISA-N
Smiles OC[C@H]1O[C@@H](N2C=CC(NC2=O)=S)[C@@H]([C@@H]1O)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 4-Thiouridine

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 26.03 100
DMSO 26.03 100

制备储备液 for 4-Thiouridine

以下数据基于产品分子量 260.26。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.84 mL 19.21 mL 38.42 mL
5 mM 0.77 mL 3.84 mL 7.68 mL
10 mM 0.38 mL 1.92 mL 3.84 mL
50 mM 0.08 mL 0.38 mL 0.77 mL

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产品说明书 for 4-Thiouridine

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for 4-Thiouridine

参考文献是支持产品生物活性的出版物。

Garibaldi et al (2017) Isolation of newly transcribed RNA using the metabolic label 4-thiouridine. Methods Mol.Biol. 1648 169 PMID: 28766297

Herzog et al (2017) Thiol-linked alkylation of RNA to assess expression dynamics. Nat.Methods 14 1198 PMID: 28945705

Schofield et al (2018) TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding. Nat.Methods 15 221 PMID: 29355846

If you know of a relevant reference for 4-Thiouridine, please let us know.

按标靶查看相关产品

关键词: 4-Thiouridine, 4-Thiouridine supplier, 4sU, tagging, photoreactive, labels, labelling, labeling, RNA, seq, sequencing, SLAM, TimeLapse, Biochemicals, and, Molecular, Biology, 7005, Tocris Bioscience

2 篇 4-Thiouridine 的引用文献

引用文献是使用了 Tocris 产品的出版物。 4-Thiouridine 的部分引用包括：

Cindy et al (2023) In vivo PAR-CLIP (viP-CLIP) of liver TIAL1 unveils targets regulating cholesterol synthesis and secretion. Nat Commun 14 3386 PMID: 37296170

Ali et al (2021) Genetic Deletion of Polo-Like Kinase 2 Induces a Pro-Fibrotic Pulmonary Phenotype. Cells 10 PMID: 33799608

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