ETA Receptors
The endothelinA receptor (ETA receptor) is a member of the endothelin receptor group of G-protein-coupled receptors that also includes ETB. They are located primarily in the vascular smooth muscle where they play a role in vasoconstriction and cell proliferation.
ETA Receptor Antagonists |
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|---|---|
| Cat. No. | Product Name / Activity |
| 5730 | A 127722 |
| Highly potent, selective ETA antagonist; orally bioavailable | |
| 5828 | Ambrisentan |
| Selective ETA antagonist | |
| 1188 | BQ-123 |
| Selective ETA antagonist | |
The endothelinA receptor (ETA receptor) is a member of the endothelin receptor group of G-protein-coupled receptors that also includes ETB. They are located primarily in the vascular smooth muscle where they play a role in vasoconstriction and cell proliferation. The human ETA receptor gene has been localized to chromosome 4 (4q31.22).