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Submit ReviewClofibrate
Description: PPAR agonist
Chemical Name: Ethyl 2-(4-chlorophenoxy)-2-methylpropionate
Biological Activity for Clofibrate
Clofibrate is a PPAR agonist (EC50 values are 50, 500 and > 100 μM at PPARα, PPARγ and PPARδ respectively). Antihyperlipoproteinemic.
Technical Data for Clofibrate
| M. Wt | 242.7017 |
| Formula | C12H15ClO3 |
| Storage | Store at RT |
| CAS Number | 637-07-0 |
| PubChem ID | 2796 |
| InChI Key | KNHUKKLJHYUCFP-UHFFFAOYSA-N |
| Smiles | ClC1=CC=C(OC(C)(C)C(OCC)=O)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Clofibrate
References for Clofibrate
References are publications that support the biological activity of the product.
Bishop-Bailey (2000) Peroxisome proliferator-activated receptors in the cardiovascular system. Br.J.Pharmacol. 129 823 PMID: 10696077
Shepherd (1993) Mechanism of action of fibrates. Postgrad.Med.J. 69 S34 PMID: 8497455
Willson et al (2000) The PPARs: from orphan receptors to drug discovery. J.Med.Chem. 43 527 PMID: 10691680
Merck Index 12 2437
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Keywords: Clofibrate, Clofibrate supplier, PPAR, agonists, Non-Selective, Peroxisome, Proliferator-activating, Receptors, Non-selective, 0824, Tocris Bioscience
⚠ WARNING: This product can expose you to chemicals including Clofibrate, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov
Citations for Clofibrate
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Currently there are no citations for Clofibrate.
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