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Submit ReviewDMNPE-caged ATP diammonium salt
Description: Caged ATP
Chemical Name: Adenosine 5'-triphosphate P"-[1-(4,5-dimethoxy-2-nitrophenyl)ethyl] ester diammonium salt
Purity: ≥98% (HPLC)
Biological Activity for DMNPE-caged ATP diammonium salt
DMNPE-caged ATP diammonium salt is a DMNPE-caged ATP; quantum yield is 0.07. Brain penetrant.
Technical Data for DMNPE-caged ATP diammonium salt
| M. Wt | 750.44 |
| Formula | C20H27N6O17P3.2NH3 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| PubChem ID | 90489017 |
| InChI Key | HPJJJBGNWXLSNQ-XZDMMRHOSA-N |
| Smiles | N.N.COC1=CC(C(C)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)=C(C=C1OC)[N+]([O-])=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for DMNPE-caged ATP diammonium salt
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 75.04 | 100 | |
| DMSO | 37.52 | 50 |
Preparing Stock Solutions for DMNPE-caged ATP diammonium salt
The following data is based on the product molecular weight 750.44. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.33 mL | 6.66 mL | 13.33 mL |
| 5 mM | 0.27 mL | 1.33 mL | 2.67 mL |
| 10 mM | 0.13 mL | 0.67 mL | 1.33 mL |
| 50 mM | 0.03 mL | 0.13 mL | 0.27 mL |
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Product Datasheets for DMNPE-caged ATP diammonium salt
References for DMNPE-caged ATP diammonium salt
References are publications that support the biological activity of the product.
Ellis-Davies (2007) Caged compounds: photorelease technology for control of cellular chemistry and physiology. Nat.Methods 4 619 PMID: 17664946
Jensen et al (2017) Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly selective and brain-penetrant 5-HT2A receptor agonist. J.Pharmacol.Exp.Ther. 36 441 PMID: 28360333
If you know of a relevant reference for DMNPE-caged ATP diammonium salt, please let us know.
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Citations for DMNPE-caged ATP diammonium salt
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
P2X and P2Y Receptors Scientific Review
Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.