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Submit ReviewPEN (mouse)
Description: GPR83 agonist
Alternative Names: pro-SAAS (221-242)
Purity: ≥95% (HPLC)
Biological Activity for PEN (mouse)
PEN (mouse) is a endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide. Activates phospholipase C (PLC)-mediated signaling cascade in mouse hypothalamus.
Technical Data for PEN (mouse)
| M. Wt | 2317.62 |
| Formula | C102H169N27O34 |
| Sequence | SVDQDLGPEVPPENVLGALLRV |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 1236955-25-1 |
| PubChem ID | 131648253 |
| InChI Key | FQPFUCOMMICWOE-CPPASMBOSA-N |
| Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for PEN (mouse)
| Solubility | Soluble to 1 mg/ml in PBS (pH 7.4) |
Product Datasheets for PEN (mouse)
References for PEN (mouse)
References are publications that support the biological activity of the product.
Gomes et al (2016) Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Sci.Signal. 9 ra43 PMID: 27117253
Mack et al (2019) Neuropeptide PEN and its receptor GPR83: distribution, signaling, and regulation. ACS Chem.Neurosci. 10 1884 PMID: 30726666
If you know of a relevant reference for PEN (mouse), please let us know.
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Keywords: PEN (mouse), PEN (mouse) supplier, GPR83, agonists, agonism, neuropeptide, JP05, GPR72, glucocorticoid-induced, receptor, pro-SAAS, (221-242), 6308, Tocris Bioscience
Citations for PEN (mouse)
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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