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Submit ReviewTocriscreen Library of FDA-Approved Compounds
Discontinued Product
This product has been withdrawn from sale and is superseded by Tocriscreen FDA-Approved Drugs Library (Cat. No. 7200)
Description: A library of 159 FDA-approved compounds (250 μL 10 mM DMSO solutions)
Biological Activity
A library of 159 compounds supplied pre-dissolved in DMSO (250 μL 10 mM solution). Contains compounds covering a range of therapeutic classes e.g. the cardiovascular and nervous systems and research areas such as cancer and immunology. Includes both established gold-standard compounds, e.g. tamoxifen, paclitaxel, as well as more recent highly selective, targeted compounds, such as gefitinib and axitinib.
Key Format and Product Details
- All compounds are FDA-approved
- Full chemical and biological data available
- 96-well racks with Matrix storage tubes & SepraSeal caps
- Compounds arranged 80 per rack with 2 racks per library
- Pre-dissolved in 250 μL 10 mM DMSO solutions
- Compounds produced to same high chemical standard as Tocris catalog
Technical Data
| Storage | Store at -20°C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
Please contact Customer Service
References
References are publications that support the biological activity of the product.
Li et al (2015) Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 17 195 PMID: 26253201
Yu et al (2015) Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell 16 142 PMID: 25658371
Edwards et al (2014) The University of New Mexico Center for Molecular Discovery. Comb.Chem.High Throughput Screen. 17 256 PMID: 24409953
Li et al (2011) Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Research 21 196 PMID: 20956998
Beacham et al (2010) Cell-based potassium ion channel screening using the FluxORTM assay. J.Biomol.Screen. 15 44 PMID: 20208034.
Hattori et al (2010) Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proc.Natl.Acad.Sci.USA 107 3546 PMID: 20142487
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Citations for Tocriscreen Library of FDA-Approved Compounds
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Tocriscreen Compound Libraries
This brochure gives an overview of the unique TocriscreenTM bioactive compound library range, including
- Tocriscreen 2.0 Compound Library
- Focused Tocriscreen Libraries
- Tocriscreen FDA-approved Drug Library
- Tocriscreen PRO Custom Service