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Submit ReviewTP 472N
Description: Negative control for TP 472
Chemical Name: 1-(8-(2-(Cyclopropylmethoxy)phenyl)pyrrolo[1,2-a]pyrimidin-6-yl)ethanone
Purity: ≥98% (HPLC)
Biological Activity for TP 472N
TP 472N is a negative control for TP 472. Inactive against other bromodomains (>20 μM against BRD9).
Active Analog also available.
Licensing Information
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the TP 472 probe summary on the SGC website.
Compound Libraries for TP 472N
TP 472N is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Epigenetics Library. Find out more about compound libraries available from Tocris.
Technical Data for TP 472N
| M. Wt | 306.36 |
| Formula | C19H18N2O2 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 2080306-24-5 |
| PubChem ID | 124201853 |
| InChI Key | IDQWBZAMTQTECP-UHFFFAOYSA-N |
| Smiles | O=C(C)C1=CC(C2=CC=CC=C2OCC3CC3)=C4N=CC=CN41 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for TP 472N
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 30.64 | 100 | |
| ethanol | 6.13 | 20 |
Preparing Stock Solutions for TP 472N
The following data is based on the product molecular weight 306.36. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.26 mL | 16.32 mL | 32.64 mL |
| 5 mM | 0.65 mL | 3.26 mL | 6.53 mL |
| 10 mM | 0.33 mL | 1.63 mL | 3.26 mL |
| 50 mM | 0.07 mL | 0.33 mL | 0.65 mL |
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Product Datasheets for TP 472N
References for TP 472N
References are publications that support the biological activity of the product.
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Keywords: TP 472N, TP 472N supplier, TP472N, Negative, control, TP, 472, Bromodomains, 5999, Tocris Bioscience
Citations for TP 472N
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