Immune Checkpoint Inhibitors

Cat. No. Product Name / Activity
4392 680C91
Potent and selective tryptophan 2,3-dioxygenase (TDO) inhibitor
7831 AUNP 12
Peptide inhibitor of the PD-1 signaling pathway
1545 (R)-(+)-Bay K 8644
TMEM176B inhibitor; activates inflammasomes; also CaV1.x blocker
6007 INCB 024360-analog
Potent indoleamine 2,3-dioxygenase (IDO) inhibitor
6068 Lin28 1632
Lin28 inhibitor; suppresses PD-L1 expression and enhances T cell-mediated antitumor immunity; also bromodomain inhibitor
5698 1-Methyl-D-tryptophan
Indoleamine 2,3-dioxygenase (IDO) inhibitor
8119 ML T7
Inhibitor of phosphatidylserine/CEACAM1 binding to Tim-3
6370 Nor NOHA monoacetate
Arginase inhibitor
6515 (D)-PPA 1
PD-1/PD-L1 interaction inhibitor
8050 SA-15-P
Dual inhibitor of LAG3 interaction with both MHCII and FGL1
6979 SEN 177
Disrupts binding of SIRP-α to CD47; potent glutaminyl cyclase inhibitor.
7533 ZE 132
Potent and selective PD-1/PD-L1 interaction inhibitor