Wnt Signaling Pathway
β-catenin β-catenin β-
catenin β-catenin PAR1 Wnt GSK-3β GSK-3β CK1ε CK1α PP2A c-Jun c-Myc Proteasomal degradation
catenin β-catenin PAR1 Wnt GSK-3β GSK-3β CK1ε CK1α PP2A c-Jun c-Myc Proteasomal degradation
The Wnt signaling pathway regulates several developmental processes such as differentiation, cell migration and proliferation during embryogenesis and in adult tissues. Dysregulation of this signaling pathway may promote tumorigenesis and metastasis.
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Signaling Pathway Key
Stimulates
Translocates
Kinase
Transcription Factor
Phosphatase
Inhibits
Other Protein
7-TM Receptor
